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Spinal Cord Injury and Traumatic Brain Injury Research Grant Program


 

Spinal Cord Injury and Traumatic Brain Injury Research Grant Program


 
The Office of Higher Education administers the Spinal Cord Injury and Traumatic Brain Injury Research Grant Program for research into new and innovative treatments and rehabilitative efforts for the functional improvement of people with spinal cord and traumatic brain injuries. Research topics may include, but are not limited to, pharmaceutical, medical device, brain stimulus, and rehabilitative approaches and techniques.

Funding Sources


The State of Minnesota established the Spinal Cord Injury and Traumatic Brain Injury Grant Program effective July 1, 2015 with a $500,000 per year appropriation. Research funding from the Legislature is split 50/50 between spinal cord injuries and traumatic brain injuries. In 2017, the legislature added an additional $5 million for the biennium to support spinal cord and traumatic brain injury research, for a total of $6,000,000 for the biennium split between the two research areas. These grant awards were also supplemented by a $15,000 program donation from the Get Up to Cure Paralysis Foundation.

Grant Recipients 2019

In May 2018, the Spinal Cord and Traumatic Brain Injury Advisory Council convened to review proposals for fiscal year 2019. As a result, nineteen projects were funded. The 2019 Spinal Cord and Traumatic Brain Injury grantees are:

Spinal Cord Injury Research

  • Mayo Clinic: Spinal Cord Tissue Regeneration through Schwann Cell Seeded Hydrogel Scaffolds with Spatial-Selective Electrical Stimulation
  • Mayo Clinic: Direct Comparison of Transcutaneous and Epidural Spinal Stimulation to Enable Motor Function in Humans with Motor Complete Paraplegia
  • Mayo Clinic: New Combinational Strategies for Regenerative Repair of the Injured Spinal Cord
  • HealthPartners Institute: Intranasal Insulin to Improve Recovery following Cervical Spinal Cord Injury
  • Hennepin Healthcare-HCMC/Minneapolis Medical Research Foundation, Minneapolis VA: iRehab: Discovering Outpatient Rehabilitative Measures for Epidural Stimulation Assisted Movement
  • Hennepin Healthcare-HCMC/Minneapolis Medical Research Foundation, University of Minnesota: iOptimize: Optimization of Epidural Stimulation for Spinal Cord Injury
  • Regents of the University of Minnesota: Targeting Estrogen Receptors to Restore Spinal Plasticity in Acute Spinal Cord Injury
  • Regents of the University of Minnesota: Training Transplanted Spinal Neuronal Progenitor Cells to Function after Chronic Spinal Cord Injury
  • Regents of the University of Minnesota: Optogenetics for Corticospinal Tract Stimulation in Combination with Transplanted Spinal Neuronal Progenitor Cells after Spinal Cord Injury

Traumatic Brain Injury Research

  • Minneapolis Medical Research Foundation & HCMC: Neuroimaging and Neurovision Rehabilitation for Neurocognitive Deficits secondary to Oculomotor Dysfunction in Mild Traumatic Brain Injury
  • Minneapolis Medical Research Foundation & HCMC: Correlation between Eyetracking and Developmental Optometry in Oculomotor Dysfunction following Traumatic Brain Injury
  • Minneapolis Medical Research Foundation, HCMC & University of Minnesota: Cortical Spreading Depolarization after Severe Traumatic Brain Injury
  • Minneapolis VA Healthcare System: Combined tDCS and Cognitive Training to Reduce Impulsivity in Patients with Traumatic Brain Injury
  • Minneapolis VA Healthcare System: Head-mounted Display Virtual Reality in the Treatment of Upper Extremity Function in Acute TBI Rehabilitation: A Comparison Study to Conventional OT Treatment
  • Regents of the University of Minnesota: Evolution of Acute and Chronic Effects on Neuronal Activity and Morphology following Mild Cerebral Cortical Traumatic Brain Injury using Multi-Scale Optical Imaging in Behaving Mice
  • Regents of the University of Minnesota: The Roles of Tau in Chronic Traumatic Encephalopathy
  • Regents of the University of Minnesota: Harnessing Exosomes as a Biomarker and Therapeutic Approach to Traumatic Brain Injury
  • Regents of the University of Minnesota: Reprogramming Astrocytes into Neurons to Provide Therapeutic Benefit to TBI
  • Minneapolis Medical Research Foundation: Acute Biomarkers for Traumatic Brain Injury Across the Severity Scale

Grant Recipients 2018

In June, 2017, the Spinal Cord and Traumatic Brain Injury Advisory Council convened to review proposals for fiscal year 2018. As a result, twelve projects were funded. The 2018 Spinal Cord and Traumatic Brain Injury grantees are:

Spinal Cord Injury Research

  • Mayo Clinic: Safety And Feasibility of Low Level Epidural Electrical Stimulation for Individuals with SCI
  • Mayo Clinic: Modulating The Spinal Cord Microenvironment And Sublesional Circuitry Using Epidural Stimulation With Electrically Conductive Hydrogel Scaffolds Seeded With Schwann Cells
  • Mayo Clinic: Metabolic Risk Factors as Targets to Improve Rehabilitation Outcomes after Spinal Cord Injury
  • Minneapolis Medical Research Foundation: Optimizing Epidural Spinal Cord Stimulation to Restore Cardiovascular Function after Spinal Cord Injury
  • Minneapolis VA Health Care System and University of Minnesota: Upper Body Dynamic Positioning System for Persons with SCI
  • University of Minnesota: Precision Placement of Spinal Neural Progenitor Cells in Patient-Specific 3D Bio-Printed Scaffolds for Chronic Spinal Cord Injury Repair
  • University of Minnesota: Accelerating The Differentiation of Human Pluripotent Stem Cells to Treat Spinal Cord Injury
  • AbiliTech Medical Inc.: Development of a Powered Hand Grip System for Quadriplegia

Traumatic Brain Injury Research

  • Minneapolis Medical Research Foundation: Effectiveness of a Neck-Strengthening Program for the Prevention or Mitigation of Sports Concussion Injuries in Student Athletes
  • Minneapolis Medical Research Foundation: Eye Tracking and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury (Mtbi)
  • University of Minnesota: Therapeutic Application of Non-Hematopoietic Umbilical Cord Blood Stem Cells (Nh­ Ucbscs) In Traumatic Brain Injury: Immune Modulation With Acute And Long Term Benefits
  • Allina Health: Exploring the Role of Combined Cognitive and Motor Dual-Task Assessment and Rehabilitation for Individuals with Residual Symptoms After mTBI

Reports

Download reports to the Minnesota Legislature on the institutions receiving grants and their purpose.